M. lignano Neoblast Screen 2016 Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano. (2016) Grudniewska M*, Mouton S*, Simanov S, Beltman F, Grelling M, de Mulder K, Arindrarto W, Weissert P, van der Elst S, Berezikov E. eLife 2016;5:e20607. Home Download

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Found 1580 results for log2(JuvG2M/JuvG1) <= -1 and fdr <= 0.05. Showing entries 1-20.

Graph Cluster Transcripts Mean logCPM Classification Smed/Human type Human gene Annotation
1. Cluster-6829.1 RNA1509_330, RNA1509_1570 8.57

RNA1509_330 {Length: 604} {Type: 5UTR_CDS_3UTR} {RNA815_5996.1} {RNA1310_64730.1}

RNA1509_1570 {Length: 671} {Type: 5UTR_CDS_3UTR} {RNA815_5996.1} {RNA1310_64730.1}
2. Cluster-7993.7950 RNA1509_1249 8.57 Neural (both ciliated and non-ciliated); Parapharyngeal; Asexual_biased; Xins GLIPR1L1 RNA1509_1249 {Length: 1276} {Type: 5UTR_CDS_3UTR} {Pfam: Cysteine-rich secretory protein family [PF00188.21, score=80.4]} {Human: GLIPR1L1, GLI pathogenesis-related 1 like 1 [Source:HGNC Symbol;Acc:28392], e=2e-26} {UniRef50_W4ZGC0, e=2e-40, Uncharacterized protein n=1 Tax=Strongylocentrotus purpuratus RepID=W4ZGC0_STRPU [Invertebrates:Echinodermata]} {Drosophila: CG8483, , e=1e-24} {Celegans: scl-11, Caenorhabditis elegans Protein SCL-11 (scl-11) mRNA, complete cds. [Source:RefSeq mRNA;Acc:NM_070098], e=1e-22} {RNA815_14337} {RNA1310_33391} {Smed: dd_Smed_v6_433_0_1,dd_Smed_v6_681_0_1,dd_Smed_v6_6756_0_1,dd_Smed_v6_7131_0_1} {WURTZEL: Neural (both ciliated and non-ciliated) [dd_Smed_v6_6756_0_1, peptidase inhibitor 15 (PI15)] ## Parapharyngeal [dd_Smed_v6_433_0_1, peptidase inhibitor 16 (PI16)]}
3. Cluster-7993.7984 RNA1509_256 8.27 Neural (both ciliated and non-ciliated); Parapharyngeal; Asexual_biased; Xins GLIPR1L1 RNA1509_256 {Length: 1610} {Type: 5UTR_CDS_3UTR} {Pfam: Cysteine-rich secretory protein family [PF00188.21, score=79.9]} {Human: GLIPR1L1, GLI pathogenesis-related 1 like 1 [Source:HGNC Symbol;Acc:28392], e=6e-26} {UniRef50_W4ZGC0, e=2e-40, Uncharacterized protein n=1 Tax=Strongylocentrotus purpuratus RepID=W4ZGC0_STRPU [Invertebrates:Echinodermata]} {Drosophila: CG8483, , e=3e-24} {RNA815_14337} {RNA1310_33391} {Smed: dd_Smed_v6_433_0_1,dd_Smed_v6_681_0_1,dd_Smed_v6_6756_0_1,dd_Smed_v6_7131_0_1} {WURTZEL: Neural (both ciliated and non-ciliated) [dd_Smed_v6_6756_0_1, peptidase inhibitor 15 (PI15)] ## Parapharyngeal [dd_Smed_v6_433_0_1, peptidase inhibitor 16 (PI16)]}
4. Cluster-7993.2977 RNA1509_178, RNA1509_182, RNA1509_1440 8.03 SULT1C4

RNA1509_178 {Length: 2285} {Type: 5UTR_CDS_3UTR} {Pfam: Sulfotransferase domain [PF00685.22, score=168.9]} {Human: SULT1C4, sulfotransferase family, cytosolic, 1C, member 4 [Source:HGNC Symbol;Acc:11457], e=2e-43} {UniRef50_O00338, e=3e-45, Sulfotransferase 1C2 n=392 Tax=Sarcopterygii RepID=ST1C2_HUMAN [Vertebrates:Chordata]} {Drosophila: St1, Sulfotransferase 1 [Source:FlyBase gene name;Acc:FBgn0034887], e=2e-22} {RNA815_6793} {RNA1310_14124}

RNA1509_182 {Length: 1908} {Type: 5UTR_CDS_3UTR} {Pfam: Sulfotransferase domain [PF00685.22, score=169.4]} {Human: SULT1C4, sulfotransferase family, cytosolic, 1C, member 4 [Source:HGNC Symbol;Acc:11457], e=7e-44} {UniRef50_O00338, e=3e-45, Sulfotransferase 1C2 n=392 Tax=Sarcopterygii RepID=ST1C2_HUMAN [Vertebrates:Chordata]} {Drosophila: St1, Sulfotransferase 1 [Source:FlyBase gene name;Acc:FBgn0034887], e=2e-22} {RNA815_6793} {RNA1310_14124}

RNA1509_1440 {Length: 1144} {Type: 5UTR_CDS_3UTR} {Pfam: Sulfotransferase domain [PF00685.22, score=171.3]} {Human: SULT1C4, sulfotransferase family, cytosolic, 1C, member 4 [Source:HGNC Symbol;Acc:11457], e=7e-46} {UniRef50_O00338, e=3e-45, Sulfotransferase 1C2 n=392 Tax=Sarcopterygii RepID=ST1C2_HUMAN [Vertebrates:Chordata]} {Drosophila: St1, Sulfotransferase 1 [Source:FlyBase gene name;Acc:FBgn0034887], e=3e-23} {Celegans: ssu-1, Caenorhabditis elegans Protein SSU-1 (ssu-1) mRNA, complete cds. [Source:RefSeq mRNA;Acc:NM_075479], e=6e-20} {RNA815_6793} {RNA1310_14124}
5. Cluster-7993.1742 RNA1509_1488 7.85 PCSK2 RNA1509_1488 {Length: 924} {Type: 5UTR_CDS_3UTR} {Pfam: Proprotein convertase P-domain [PF01483.15, score=52.9]} {Human: PCSK2, proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:8744], e=3e-19} {UniRef50_Q5C2Y4, e=2e-30, SJCHGC02735 protein (Fragment) n=1 Tax=Schistosoma japonicum RepID=Q5C2Y4_SCHJA [Invertebrates:Platyhelminthes]} {Drosophila: amon, amontillado [Source:FlyBase gene name;Acc:FBgn0023179], e=9e-24} {RNA815_2403.1} {RNA1310_7333.1}
6. Cluster-9578.0 RNA1509_2352, RNA1509_2885, RNA1509_3088, RNA1509_17618, RNA1509_34299 7.83

RNA1509_2352 {Length: 713} {Type: 5UTR_CDS_3UTR} {Pfam: UPF0506 [PF11703.3, score=33.8]} {RNA815_11592} {RNA1310_51767.1}

RNA1509_2885 {Length: 651} {Type: 5UTR_CDS_3UTR} {Pfam: UPF0506 [PF11703.3, score=34.1]} {RNA815_11592} {RNA1310_51767.2}

RNA1509_3088 {Length: 1179} {Type: 5UTR_CDS_3UTR} {Pfam: UPF0506 [PF11703.3, score=32.5]} {RNA815_11592} {RNA1310_51767.1}

RNA1509_17618 {Length: 1171} {Type: 5UTR_CDS_3UTR} {Pfam: UPF0506 [PF11703.3, score=32.5]} {RNA815_11592} {RNA1310_51767.1}

RNA1509_34299 {Length: 1140} {Type: 5UTR_CDS_3UTR} {Pfam: UPF0506 [PF11703.3, score=32.5]} {RNA815_11592} {RNA1310_51767.1}
7. Cluster-12543.1 RNA1509_4179, RNA1509_22134 7.71

RNA1509_4179 {Length: 1051} {Type: 5UTR_CDS_3UTR} {RNA815_21638.1} {RNA1310_50528}

RNA1509_22134 {Length: 616} {Type: 5UTR_CDS_3UTR} {RNA815_33105} {RNA1310_50528}
8. Cluster-15355.3 RNA1509_7665, RNA1509_23529 7.71 NEU4

RNA1509_7665 {Length: 476} {Type: 5UTR_CDS_3UTR} {RNA815_29000} {RNA1310_89635.1}

RNA1509_23529 {Length: 768} {Type: 5UTR_CDS_3UTR} {Human: NEU4, sialidase 4 [Source:HGNC Symbol;Acc:21328], e=0.006} {UniRef50_F8UKT5, e=1e-08, FMRFamide neuropeptide n=1 Tax=Platynereis dumerilii RepID=F8UKT5_PLADU [Invertebrates:Annelida]} {RNA815_29000} {RNA1310_89635.1}
9. Cluster-7993.3831 RNA1509_303 7.64 Neural (non-ciliated); Asexual_biased; Xins SYT11 RNA1509_303 {Length: 2712} {Type: 5UTR_CDS_3UTR} {Pfam: C2 domain [PF00168.25, score=156.8]} {Human: SYT11, synaptotagmin XI [Source:HGNC Symbol;Acc:19239], e=8e-87} {UniRef50_B7PXT8, e=1e-137, Synaptotagmin, putative n=5 Tax=Bilateria RepID=B7PXT8_IXOSC [Invertebrates:]} {Drosophila: Syt4, Synaptotagmin 4 [Source:FlyBase gene name;Acc:FBgn0028400], e=1e-100} {RNA815_4825} {RNA1310_7615} {Smed: dd_Smed_v6_7243_0_1} {WURTZEL: Neural (non-ciliated) [dd_Smed_v6_7243_0_1, synaptotagmin XI (SYT11)]}
10. Cluster-7993.1884 RNA1509_98, RNA1509_128, RNA1509_1132 7.64

RNA1509_98 {Length: 913} {Type: 5UTR_CDS_3UTR} {Pfam: Protein of unknown function (DUF3421) [PF11901.3, score=121.0]} {UniRef50_G4V7P2, e=2e-30, Putative uncharacterized protein n=8 Tax=Digenea RepID=G4V7P2_SCHMA [Plants:]} {Drosophila: CG13321, , e=1e-18} {RNA815_908.2} {RNA1310_39489}

RNA1509_128 {Length: 1043} {Type: 5UTR_CDS_3UTR} {Pfam: Protein of unknown function (DUF3421) [PF11901.3, score=119.7]} {UniRef50_G4V7P2, e=2e-30, Putative uncharacterized protein n=8 Tax=Digenea RepID=G4V7P2_SCHMA [Plants:]} {Drosophila: CG13321, , e=3e-18} {RNA815_908.2} {RNA1310_39489}

RNA1509_1132 {Length: 1026} {Type: 5UTR_CDS_3UTR} {Pfam: Protein of unknown function (DUF3421) [PF11901.3, score=119.9]} {UniRef50_G4V7P2, e=2e-30, Putative uncharacterized protein n=8 Tax=Digenea RepID=G4V7P2_SCHMA [Plants:]} {Drosophila: CG13321, , e=2e-18} {RNA815_908.2} {RNA1310_39489}
11. Cluster-2111.0 RNA1509_910 7.49 Neural (non-ciliated); Xins; Pluripotency self-renewal PAM RNA1509_910 {Length: 1717} {Type: 5UTR_CDS_3UTR} {Pfam: NHL repeat [PF01436.16, score=96.0]} {Human: PAM, peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:8596], e=5e-54} {UniRef50_A0A0B7AXT5, e=6e-71, Uncharacterized protein n=1 Tax=Arion vulgaris RepID=A0A0B7AXT5_9EUPU [Invertebrates:Mollusca]} {Drosophila: Pal2, Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2 [Source:FlyBase gene name;Acc:FBgn0262728], e=1e-57} {RNA815_736.1} {RNA1310_18216.1} {Smed: dd_Smed_v6_3093_0_1} {WURTZEL: Neural (non-ciliated) [dd_Smed_v6_3093_0_1, peptidylglycine alpha-amidating monooxygenase (PAM)]}
12. Cluster-7993.10534 RNA1509_576 7.46 Muscle; Asexual_biased; Xins MYL12A RNA1509_576 {Length: 2749} {Type: 5UTR_CDS_3UTR} {tRNA: Pseudo(CAC),euk, score=25.30} {Pfam: EF-hand domain pair [PF13499.1, score=47.4]} {Human: MYL12A, myosin, light chain 12A, regulatory, non-sarcomeric [Source:HGNC Symbol;Acc:16701], e=2e-57} {UniRef50_A0A075A7F5, e=5e-84, Uncharacterized protein n=1 Tax=Opisthorchis viverrini RepID=A0A075A7F5_9TREM [Invertebrates:Platyhelminthes]} {Drosophila: sqh, spaghetti squash [Source:FlyBase gene name;Acc:FBgn0003514], e=3e-56} {RNA815_2093.1} {RNA1310_16012.1} {Smed: dd_Smed_v6_445_0_1,dd_Smed_v6_803_0_1} {WURTZEL: Muscle [dd_Smed_v6_445_0_1, unknown] ## Muscle [dd_Smed_v6_803_0_1, myosin, light chain 12B, regulatory (MYL12B)]}
13. Cluster-7993.1739 RNA1509_185 7.45 Neural (non-ciliated); Asexual_biased; Xins PCSK2 RNA1509_185 {Length: 2759} {Type: 5UTR_CDS_3UTR} {Pfam: Subtilase family [PF00082.17, score=187.1]} {Human: PCSK2, proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:8744], e=0.0} {UniRef50_F1NUG0, e=0.0, Uncharacterized protein n=32 Tax=Bilateria RepID=F1NUG0_CHICK [Invertebrates:]} {Drosophila: amon, amontillado [Source:FlyBase gene name;Acc:FBgn0023179], e=0.0} {RNA815_2403.2} {RNA1310_7333.1} {Smed: dd_Smed_v6_1566_0_1} {WURTZEL: Neural (non-ciliated) [dd_Smed_v6_1566_0_1, prohormone convertase 2]}
14. Cluster-11233.6 RNA1509_2727, RNA1509_46771 7.45 SLC16A14

RNA1509_2727 {Length: 1904} {Type: 5UTR_CDS_3UTR} {RNA815_9650} {RNA1310_12162}

RNA1509_46771 {Length: 2399} {Type: 5UTR_CDS_3UTR} {Pfam: Major Facilitator Superfamily [PF07690.11, score=108.0]} {Human: SLC16A14, solute carrier family 16, member 14 (monocarboxylic acid transporter 14) [Source:HGNC Symbol;Acc:26417], e=1e-24} {UniRef50_V4ADB8, e=2e-84, Uncharacterized protein (Fragment) n=1 Tax=Lottia gigantea RepID=V4ADB8_LOTGI [Invertebrates:Mollusca]} {Drosophila: Mct1, Monocarboxylate transporter 1 [Source:FlyBase gene name;Acc:FBgn0023549], e=1e-70} {RNA815_9650} {RNA1310_12162}
15. Cluster-13285.2 RNA1509_891, RNA1509_14636, RNA1509_28514, RNA1509_56572 7.34

RNA1509_891 {Length: 1432} {Type: 5UTR_CDS_3UTR} {UniRef50_L1ITI2, e=2e-06, Uncharacterized protein n=1 Tax=Guillardia theta CCMP2712 RepID=L1ITI2_GUITH [Plants:]} {RNA815_10418.2} {RNA1310_24129}

RNA1509_14636 {Length: 1429} {Type: 5UTR_CDS_3UTR} {UniRef50_L1ITI2, e=2e-06, Uncharacterized protein n=1 Tax=Guillardia theta CCMP2712 RepID=L1ITI2_GUITH [Plants:]} {RNA815_10418.2} {RNA1310_24129}

RNA1509_28514 {Length: 1537} {Type: 5UTR_CDS_3UTR} {UniRef50_L1ITI2, e=2e-06, Uncharacterized protein n=1 Tax=Guillardia theta CCMP2712 RepID=L1ITI2_GUITH [Plants:]} {RNA815_10418.2} {RNA1310_24129}

RNA1509_56572 {Length: 1427} {Type: 5UTR_CDS_3UTR} {UniRef50_L1ITI2, e=1e-06, Uncharacterized protein n=1 Tax=Guillardia theta CCMP2712 RepID=L1ITI2_GUITH [Plants:]} {RNA815_10418.2} {RNA1310_24129}
16. Cluster-7993.1887 RNA1509_386, RNA1509_18673 7.3

RNA1509_386 {Length: 813} {Type: 5UTR_CDS_3UTR} {Pfam: Protein of unknown function (DUF3421) [PF11901.3, score=122.2]} {UniRef50_G4V7P2, e=2e-30, Putative uncharacterized protein n=8 Tax=Digenea RepID=G4V7P2_SCHMA [Plants:]} {Drosophila: CG13321, , e=8e-19} {RNA815_16771} {RNA1310_20215}

RNA1509_18673 {Length: 1309} {Type: 5UTR_CDS_3UTR} {Pfam: Protein of unknown function (DUF3421) [PF11901.3, score=99.1]} {UniRef50_G4V7P2, e=2e-30, Putative uncharacterized protein n=8 Tax=Digenea RepID=G4V7P2_SCHMA [Plants:]} {Drosophila: CG13321, , e=6e-18} {RNA815_16771} {RNA1310_20215}
17. Cluster-15790.28 RNA1509_333, RNA1509_406 7.19 Gut; Asexual_biased; Sexual_biased; Xins TSPAN18

RNA1509_333 {Length: 1706} {Type: 5UTR_CDS_3UTR} {Pfam: Tetraspanin family [PF00335.15, score=138.5]} {Human: TSPAN18, tetraspanin 18 [Source:HGNC Symbol;Acc:20660], e=5e-19} {UniRef50_D6X4U5, e=3e-29, Tetraspanin n=2 Tax=Tribolium castaneum RepID=D6X4U5_TRICA [Invertebrates:Arthropoda]} {Drosophila: Tsp66E, Tetraspanin 66E [Source:FlyBase gene name;Acc:FBgn0035936], e=2e-21} {RNA815_7133.1} {RNA1310_21956} {Smed: dd_Smed_v6_354_0_1} {WURTZEL: Gut [dd_Smed_v6_354_0_1, tetraspanin 3 (TSPAN3)]}

RNA1509_406 {Length: 1659} {Type: 5UTR_CDS_3UTR} {Pfam: Tetraspanin family [PF00335.15, score=138.6]} {Human: TSPAN18, tetraspanin 18 [Source:HGNC Symbol;Acc:20660], e=5e-19} {UniRef50_D6X4U5, e=3e-29, Tetraspanin n=2 Tax=Tribolium castaneum RepID=D6X4U5_TRICA [Invertebrates:Arthropoda]} {Drosophila: Tsp66E, Tetraspanin 66E [Source:FlyBase gene name;Acc:FBgn0035936], e=1e-21} {RNA815_7133.1} {RNA1310_19711} {Smed: dd_Smed_v6_354_0_1} {WURTZEL: Gut [dd_Smed_v6_354_0_1, tetraspanin 3 (TSPAN3)]}
18. Cluster-4175.0 RNA1509_1053, RNA1509_1110, RNA1509_1758 7.17

RNA1509_1053 {Length: 1404} {Type: 5UTR_CDS_3UTR} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.8, score=32.2]} {RNA815_14544} {RNA1310_34072.1}

RNA1509_1110 {Length: 1293} {Type: 5UTR_CDS_3UTR} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.8, score=32.3]} {RNA815_14544} {RNA1310_34072.1}

RNA1509_1758 {Length: 1204} {Type: 5UTR_CDS_3UTR} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.8, score=27.4]} {RNA815_14544} {RNA1310_34072.1}
19. Cluster-9437.0 RNA1509_811 7.17 ADAMTS6 RNA1509_811 {Length: 1813} {Type: 5UTR_CDS_3UTR} {Pfam: Metallo-peptidase family M12 [PF13688.1, score=52.3]} {Human: ADAMTS6, ADAM metallopeptidase with thrombospondin type 1 motif, 6 [Source:HGNC Symbol;Acc:222], e=2e-12} {UniRef50_K1PUB4, e=6e-39, ADAM family mig-17 n=1 Tax=Crassostrea gigas RepID=K1PUB4_CRAGI [Invertebrates:Mollusca]} {Drosophila: CG9850, , e=2e-12} {RNA815_7066} {RNA1310_18102.1}
20. Cluster-7067.2 RNA1509_380 7.11 Pluripotency repressor ADAMTS1 RNA1509_380 {Length: 1869} {Type: 5UTR_CDS_3UTR} {Pfam: Metallo-peptidase family M12 [PF13688.1, score=50.3]} {Human: ADAMTS1, ADAM metallopeptidase with thrombospondin type 1 motif, 1 [Source:HGNC Symbol;Acc:217], e=6e-15} {UniRef50_K1PUB4, e=1e-32, ADAM family mig-17 n=1 Tax=Crassostrea gigas RepID=K1PUB4_CRAGI [Invertebrates:Mollusca]} {Drosophila: CG9850, , e=1e-12} {RNA815_5216} {RNA1310_14719}
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